Conventional Multipoint Nonparametric Linkage Analysis Is Not Necessarily Inherently Biased
نویسندگان
چکیده
منابع مشابه
Parametric and nonparametric linkage analysis: a unified multipoint approach.
In complex disease studies, it is crucial to perform multipoint linkage analysis with many markers and to use robust nonparametric methods that take account of all pedigree information. Currently available methods fall short in both regards. In this paper, we describe how to extract complete multipoint inheritance information from general pedigrees of moderate size. This information is captured...
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ژورنال
عنوان ژورنال: The American Journal of Human Genetics
سال: 2004
ISSN: 0002-9297
DOI: 10.1086/424755